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Ligaplex II - 150 capsules
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These products are available exclusively to current CHM patients and should be used under the guidance of their CHM healthcare provider. To purchase, please enter the product name(s) and quantity in the Order Notes section at checkout. A member of our CHM team will review your request and send an invoice for payment.
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Description
Description
Ligaplex II supports tissue and joints to maintain connective tissue health, especially for long-term support.*
- Provides the foundation to feed the musculoskeletal system and facilitate freedom of movement
- Nutritional compounds for support of proper formation and maintenance of skeletal tissues
- Involved in maintenance of healthy fluid levels
- Contains bovine heart PMG™ extract
- Contains a combination of key ingredients from Cyro-Yeast®, Cardiotrophin PMG®, Ostrophin PMG®,Manganese B12TM , Super-EFF®, and Cataplex® E*
How does Ligaplex II help maintain a healthy skeletal system?
Ligaplex II contains bone-supporting whole food ingredients like bovine bone and veal bone. Bovine bone and veal bone PMG™ extract are used to support healthy connective tissue. A study showed that treating bone cells (mouse pre-osteoblast cells) grown under laboratory conditions with bovine bone supplements resulted in increased proliferation of bone-forming cells (osteoblasts) and accumulation of hardened (mineralized) bone material. 1*
Bone tissue serves as a reservoir of calcium and helps the body maintain a constant level of Ca+2 ions.2 It is important to understand that calcium is required throughout the human life cycle, a proper supply is required for overall health, calcium requirements change over time, and calcium inadequacies at various stages in life may result in a loss of bone density.3 Vitamin D is required by the body to absorb and mobilize calcium and also assists in natural immune modulation in the body.4 An important function of vitamin A is cellular differentiation and tissue repair.5Manganese plays a role in stimulating the creation of new bone material and calcification of bones, helps adults maintain a healthy skeleton,6 and facilitates the formation of connective tissue in the body.7 Some cellular processes, such as lipid, carbohydrate, and protein metabolism, are dependent on manganese; manganese is used by many enzymes in the body.8 Vitamin C is essential for collagen synthesis9 and collagen matrix quality.10*
How does this product support healthy fluid levels?
In the body, carbamide (urea) plays a key role in the concentration of urine. Along with sodium chloride, urea helps support healthy concentration of urine.11 The maintenance of proper fluid levels in the tissues surrounding joints helps keep them healthy.12*
How does bovine heart PMG™ extract support healthy tissues?
Bovine heart PMG™ extract is a complex raw material. This ingredient distills the complexity of the heart tissue to support human heart muscle function.*
Additional Information
Additional Information
Return Policy
Return Policy
We are committed to offering the highest-qualitynutritional supplements available. Many of our formulations are unique, physician-developed, patented, or patent-pending, and are carefully selected to meet the standards we expect for our own patients and families. Customer satisfaction is extremely important to us. If you believe a product exchange or office credit may be appropriate, please contact our Customer Service team.*
Requests must be made within 30 days of purchase and are reviewed on a case-by-case basis. Proof of purchase is required. Product exchanges and office credits may be offered when appropriate. Refunds are not provided.
For assistance, please call 866-877-6467 or email us at: info@centerforholisticmedicine.com.
We appreciate your business. Thank you!
* Please note that Dr. David Brownstein’s books are not eligible for exchange, office credit, or refund.
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Quality-focused formulations
Trusted since 1998

Established since 1998
For more than 25 years, the Center for Holistic Medicine has been dedicated to helping patients address the root causes of illness through personalized, integrative care grounded in clinical experience and evidence-based medicine.
State-licensed physicians
Our supplements and protocols are developed by experienced, state-licensed physicians who have spent decades caring for patients and advancing the field of holistic and integrative medicine.
Practitioner-grade quality
Every PureZen™ formula is carefully selected and developed with a focus on purity, effectiveness, and clinical relevance — using high-quality ingredients trusted in real-world patient care.

